Recommended follow-up for hereditary breast and ovarian cancer

Beatriz SanchezA. PARPi are recommended as maintenance therapy in patients with relapsed platinum-sensitive high-grade serous ovarian cancer IA. The appropriateness of imaging scheduling is still controversial. Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers:

Recommended follow-up for hereditary breast and ovarian cancer
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SEOM clinical guidelines in Hereditary Breast and ovarian cancer

Ann Oncol. Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly ADP-ribose polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer. LastraJ. Oral contraceptives protect against ovarian cancer IIBbut caution should be used when considering use of oral contraceptives in mutation carriers because the conflicting results on their effect on breast cancer risk.

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Recommended follow-up for hereditary breast and ovarian cancer
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Beatriz Sanchez. SerranoA. It is associated with a high lifetime risk of cancer, most diagnosed at young age as bone and soft tissue sarcoma, premenopausal breast cancer, acute leukaemia, colon cancer, adrenal cortex carcinoma, brain tumours and ovarian cancer.

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Recommended follow-up for hereditary breast and ovarian cancer
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Recommended follow-up for hereditary breast and ovarian cancer

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